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Applications of minimally invasive n...
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Mohammad Hadi, Layla.
Applications of minimally invasive nanomedicine-based therapies in 3D in vitro cancer platforms
紀錄類型:
書目-語言資料,印刷品 : 單行本
作者:
Mohammad HadiLayla.,
其他作者:
Mohammad-HadiMarym.,
出版地:
[San Rafael, California]
出版者:
Morgan & Claypool Publishers;
出版年:
c2021.
面頁冊數:
xv, 93 p.ill. : 24 cm.;
集叢名:
Synthesis lectures on materials and opticslecture #6
標題:
Cancer - Treatment -
標題:
Cancer - Photochemotherapy -
標題:
Cancer - Phototherapy -
標題:
Nanomedicine. -
摘要註:
"Minimally invasive techniques such as Photodynamic Therapy (PDT) and Photochemical Internalisation (PCI) have for years been under investigation for the treatment of solid cancers. A significant number of the recent research studies have applied PDT and PCI to biological three-dimensional (3D) cancer platforms with many of the studies also involving the use of nanoparticles in order to enhance the efficacy of these light-based therapies. Interest in the employment of 3D cancer platforms has increased considerably due to the ability of the platforms to mimic in vivo models better than the conventional two-dimensional (2D) cultures. Some of the advantages of the 3D cancer systems over their 2D counterparts include improved interaction between cancer cells and the surrounding extracellular matrix (ECM) as well as restricted drug penetration which would allow optimization of treatments prior to undertaking of in vivo studies. The different chapters of this book will discuss photosensitizers and nanoparticles used in PDT and PCI in addition to the applications of these treatments in various 3D cancer models."--Back cover.
ISBN:
9781681739694
內容註:
1. Introduction 1.1. Introduction 1.2. References 2. Photodynamic therapy and photochemical internalization 2.1. Introduction 2.2. Photodynamic therapy 2.3. Light sources used in PDT 2.4. Clinical trials of PDT in cancer patients 2.5. Clinical trials in non-cancerous diseases 2.6. Photochemical internalization 2.7. Different mechanisms of endocytosis 2.8. Clinical trials of PCI 2.9. Potential advantages of PCI over PDT 2.10. References 3. Photosensitizers and therapeutic agents used in PDT and PCI 3.1. Introduction 3.2. Photosensitizers used in PDT. 3.3. Photosensitizers used in PCI 3.4. Chemotherapeutic drugs used in PCI 3.5. PCI for the delivery of genetic material into cells 3.6. Viral gene delivery through PCI 3.7. PCI in cancer vaccination 3.8. References 4. The use of nanoparticles in PDT and PCI 4.1. Introduction 4.2. Roles of different nanoparticles in PDT and PCI 4.3. Biodegradable nanoparticles 4.4. Non-biodegradable nanoparticles 4.5. References 5. 3D in vitro cancer models. 5.1. Introduction 5.2. Three-dimensional (3D) in vitro cell culture models 5.3. References 6. The applications of PDT and PCI in 3D in vitro cancer models 6.1. Introduction 6.2. PDT in 3D cancer models 6.3. Application of PDT involving nanoparticles in 3D cancer models 6.4. PCI in 3D cancer models 6.5. References.
Applications of minimally invasive nanomedicine-based therapies in 3D in vitro cancer platforms
Mohammad Hadi, Layla.
Applications of minimally invasive nanomedicine-based therapies in 3D in vitro cancer platforms
/ Layla Mohammad-Hadi and Marym Mohammad-Hadi. - [San Rafael, California] : Morgan & Claypool Publishers, c2021.. - xv, 93 p. ; ill. ; 24 cm.. - (Synthesis lectures on materials and optics ; lecture #6).
1. Introduction.
Includes bibliographical references..
ISBN 9781681739694ISBN 1681739690ISBN 9781681739717ISBN 1681739712
CancerCancerCancerNanomedicine. -- Treatment -- Photochemotherapy -- Phototherapy
Mohammad-Hadi, Marym.
Applications of minimally invasive nanomedicine-based therapies in 3D in vitro cancer platforms
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